Researchers commonly investigate Semaglutide in studies involving GLP-1 receptor activation, glucose metabolism, insulin signaling, appetite regulation, gastrointestinal function, and metabolic disease models
Lexnatide (reprsent en rouge sur la figure 1, entre de la banque de donnes des protines (PDB) 7LLL), a t le premier agoniste du rcepteur GLP-1 approuv par lAgence amricaine des produits alimentaires et mdicamenteux (FDA, Food and Drug Administration en anglais)
By decreasing the stemness of cancer cells, GLS inhibition decreases their resistance to radiation, thus enhancing the radiosensitivity of prostate cancer
however, most phase III clinical studies are of insufficient duration and do not include enough study participants to effectively gauge long-term safety